Science Fair Project Encyclopedia
Baclofen
Baclofan is a derivative of gamma-aminobutyric acid, and is a specific to GABA-B receptors. It is used for the treatment of spastic movement, especially in instances of spinal cord injury. Its beneficial effects result from actions at spinal and supraspinal sites.
Its chemical name is 4- amino-3- (4-chlorophenyl)- butanoic acid.
Baclofen is a white to off-white, odorless or practically odorless crystalline powder, with a molecular weight of 213.66. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform.
Symptoms of a baclofen overdose include vomiting, weakness, drowsiness, slow breathing, seizures, unusual pupil size, and coma.
10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details