Events

• Tirant Lo Blanc by Joanot Martorell, Martí Joan De Galba is published.
• Yoshitane becomes Ashikaga shogun of Japan.
• Charles John Amadeus of Savoy becomes Duke of Savoy at age 1, mother Blanche of Montferrato is regent.
• Aldus Manutius moves to Venice.
• John Colet receives M.A. from Magdalen College, Oxford.
• Castle Church in Wittenberg is begun.
• Pedro de Covilham arrives in Ethiopia.
• Catholic missionaries arrive in the African kingdom of Kongo.
• Regular postal service connects the Habsburg residences of Mechelen and Innsbruck, the first in Germany.

Births

• March 24 - Georg Agricola, German scholar, scientist (+ 1555)
• May 16 - Albert, Duke of Prussia (+ 1568)
• June 28 - Albert of Mainz, elector, archbishop
• October 12 - Bernardo Pisano, Italian composer
• Marianoela Accorso, Italian scholar
• Vittoria Colonna, Italian poetess (+ 1547)
• Jean Salmon Macri , poet (+ 1557)
• Andrej Perlah , Slovene mathematician
• Philip, Duke of Nemours , son of Philip II of Savoy
• Bernhard von Reesen Gdansk merchant (approximate date)
• Kaspar Schwenkfeld von Ossig, German theologian (+ 1561)
• John Taverner, English composer (approximate date)
• Leonhard Kleber , German organist (approximate date)
• Thomas Crecquillon, French composer (approximate date)
• Claudin de Sermisy , French chanson composer (approximate date)
• Adrian Willaert, Franco-Flemish composer, the founder of the Venetian school (approximate date)

Deaths

• January 27 - Ashikaga Yoshimasa, Ashikaga shogun
• Charles I of Savoy